What is HLA-A positive?

For example, one type of HLA-A protein (HLA-A*1101) is associated with a higher risk of developing type 1 diabetes. Another type of HLA-A protein (HLA-A*02) is associated with a lower risk of getting acute myelogenous leukemia, multiple sclerosis, and chronic lymphocytic leukemia. You may not understand what this means if you are not a researcher. Scientists know why this happens, however. The HLA-A proteins help your immune system destroy infected cells and bacteria. This protein is also associated with a higher risk of heart attack. Because of the HLA-A protein, white blood cells travel around your body destroying HLA-A unwanted bacteria and viruses. These cells also destroy some other cells in your body such as fat cells and bone cells. Your body can make HLA-A proteins to fight against different diseases. However, sometimes the HLA-A proteins get into a condition called antigen-binding groove which blocks the HLA-A protein from doing its job. In such cases, the HLA-A protein stops working. This causes a problem for your immune system. That is why researchers have developed some treatments that will prevent or lessen the severity of these types of diseases.

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